Myocardial fat deposits and osteopoikilosis in tuberous sclerosis
Imaging findings
CT chest shows multiple focal, well-defined fatty deposits within the myocardium, particularly in the interventricular septum and left ventricle. Scattered sclerotic bone lesions (osteopoikilosis-like) are also present in the spine and sternum. No features of lymphangioleiomyomatosis (LAM) are seen.
Key takeaways
Myocardial fatty deposits are a recognized manifestation of tuberous sclerosis, representing either lipomatous metaplasia of rhabdomyomas or hamartomas. They are typically asymptomatic and non-arrhythmogenic, and their presence helps differentiate tuberous sclerosis from sporadic LAM.
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