CTICasesExtramedullary Hematopoiesis in Thalassemia
Imaging findings
Large, soft paraspinal masses on both sides of the spine. Dilated, expanded ribs and vertebral bodies with a speckled, granular texture. Features are characteristic of high-output marrow stimulation, sometimes showing fatty replacement depending on the stage of treatment.
Key takeaways
Extramedullary hematopoiesis should be considered in patients with thalassemia presenting with paraspinal masses. These masses are distinct from solid tumors like schwannomas as they often contain soft tissue and fat and demonstrate characteristic bone changes.
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