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Fibrosing Sarcoidosis Mimicking UIP and NSIP

Imaging findings

Upper lobes show a UIP-like pattern, while lower zones show NSIP-like subpleural sparing with traction bronchiectasis and no honeycombing. Older imaging shows perilymphatic nodules throughout the lower zones, along the fissures, and mediastinal and hilar lymphadenopathy. The pulmonary arteries are enlarged.

Key takeaways

Fibrosing sarcoidosis can look like IPF or idiopathic NSIP, so the pattern and its tempo must be read against earlier imaging. Perilymphatic nodules, fissural nodules and lymphadenopathy are the clues. Traction bronchiectasis that replaces subpleural sparing, rather than honeycombing, reflects the disease and not dilated airways.

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