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Pulmonary Amyloidosis

Imaging findings

Massive interlobular septal thickening and focal large opacities, which were FDG-avid.

Key takeaways

Septal amyloidosis should be considered when significant, non-edematous septal thickening is present. It can show FDG uptake and potentially lead to secondary cystic lung disease via giant cell-mediated matrix metalloproteinase release.

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