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Cystic Pulmonary Metastases from Uterine Sarcoma

Cystic Pulmonary Metastases from Uterine Sarcoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph and CT show numerous well-defined, thin-walled cystic lesions of varying sizes, interspersed with solid nodules throughout both lungs in a patient with a pelvic mass. Pathology of the primary pelvic mass confirmed a uterine sarcoma.

Key takeaways

Pulmonary metastases from mesenchymal tumors, particularly uterine sarcomas, can present with thin-walled cystic lesions alongside typical solid nodules. The proposed mechanism for these cystic metastases is a ball-valve phenomenon where tumor growth adjacent to small airways causes focal airway obstruction and alveolar expansion. In any patient with multifocal cystic lung disease and solid nodules, sarcoma metastases should be considered.

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