CTICasesCiliated Muconodular Papillary Tumor (CMPT) of the Lung
Imaging findings
CT demonstrates a small, slowly enlarging subpleural nodule in a patient with known melanoma. The nodule had been present since 2015 and showed slow growth by 2017 with some surrounding soft tissue change. It did not resemble a typical melanoma metastasis in its growth rate or appearance. CT-guided biopsy yielded adenocarcinoma on FNA cytology; surgical resection revealed a ciliated muconodular papillary tumor (CMPT).
Key takeaways
Ciliated muconodular papillary tumor (CMPT) is a rare benign or low-grade lung neoplasm that can mimic adenocarcinoma on FNA cytology due to the presence of mucinous and papillary epithelial cells. It is defined by a characteristic triad of ciliated cells, mucous cells, and basal cells on pathology. CT typically shows a small peripheral subpleural nodule. CMPT has an excellent prognosis after surgical resection and should not be treated as a malignant adenocarcinoma despite the FNA cytologic overlap. It will not be diagnosed prospectively by imaging alone.
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