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Hepatopleural Fistula after Microwave Ablation of Hepatocellular Carcinoma

Imaging findings

Baseline CT in a 35-year-old with hepatocellular carcinoma shows cirrhosis and portal venous hypertension, with an ablation track running from the treated lesion up to the chest wall and a small pleural effusion on the concurrent chest CT. Four days later, CT angiography for chest pain shows a large effusion with a hydropneumothorax, an air-fluid level, and trapped lung. Delayed-phase imaging through the abdomen tracks the ablated necrotic area communicating across the diaphragm into the pleural space, confirmed on coronal reconstruction as a channel running up from the liver into the pleural cavity.

Key takeaways

A new hydropneumothorax days after hepatic ablation raises several possibilities — lung puncture during the procedure, or a biliothorax — and the distinguishing evidence came from a later phase of imaging rather than from the arterial study. Delayed-phase abdominal images demonstrated the ablation cavity communicating across the diaphragm, establishing a hepatopleural fistula. The case illustrates the value of reviewing all available phases rather than the single phase ordered for the presenting question.

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