CTICasesNSIP to UIP Progression in Mixed Connective Tissue Disease
Imaging findings
Progressive fibrotic interstitial lung disease starting with a pattern typical of NSIP (2013) that evolved into a pathologically proven UIP pattern (2017) over four years.
Key takeaways
UIP is a pattern of injury rather than a single disease. In the context of autoimmune diseases, NSIP can slowly progress to a UIP pattern. Early imaging is critical for understanding the evolution of fibrotic disease.
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