CTICasesIgG4-Related Sclerosing Disease
Imaging findings
Multiple solid and part-solid nodules with a 'smudgy' or stellate appearance. Some lesions show a perilymphatic distribution, mimicking sarcoidosis, while others are associated with airways or vessels. Background emphysema was noted in one patient.
Key takeaways
IgG4-related disease should be considered in the differential diagnosis for multiple pulmonary nodules, even if they mimic sarcoidosis or other granulomatous diseases. Pathologic confirmation with IgG staining is required for diagnosis.
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