CTICasesEVALI with Pneumomediastinum (Macklin Effect)
Imaging findings
CT in a young marijuana vaper demonstrates bilateral, peribronchovascular-sparing ground-glass opacities typical of EVALI, with superimposed extensive pneumomediastinum tracking air along the bronchovascular bundles into the mediastinum (Macklin phenomenon), extra-pleural air, and a developing pneumothorax.
Key takeaways
EVALI (e-cigarette or vaping product use-associated lung injury) can be complicated by the Macklin effect (alveolar rupture with air dissecting along bronchovascular sheaths into the mediastinum), resulting in pneumomediastinum and pneumothorax. The Macklin phenomenon is more common with severe alveolar injury and high airway pressures. Its presence in EVALI can complicate clinical management.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Type A Aortic Intramural Hematoma Misdiagnosed as AortitisVascular
- Aortic Root Pseudoaneurysm after Bioprosthetic Aortic Valve ReplacementIatrogenic
- Pancreatitis with Pancreatic Pseudocyst Eroding through the DiaphragmInflammatory
- Thymoma (B3) with Intraperitoneal and Pelvic Drop MetastasesNeoplastic
- Hepatopulmonary Syndrome Type 2 with Pulmonary Vascular NodulesVascular
- Ascending Aortic Graft Dehiscence with Chest Wall ErosionIatrogenic
- Type III Endoleak after Thoracic Endovascular Aortic Repair (TEVAR)Iatrogenic
- Invasive Aspergillosis with Concurrent Pneumocystis jirovecii PneumoniaInfection
See all cases from March 19, 2021 →