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Bilateral Thick-Walled Cavities from Alpha-Hemolytic Streptococcal Infection after Hookah Smoking

Imaging findings

CT demonstrates bilateral thick-walled cavitary lesions in both upper lobes in a 60-year-old woman transferred for suspected tuberculosis. Bronchoscopy was negative for fungal infection and tuberculosis. History revealed frequent visits to hookah bars using wet tobacco mouthpieces that grew alpha-hemolytic Streptococcus. Follow-up CT one month later shows improvement of the cavitary lesions with antibiotic treatment.

Key takeaways

Hookah smoking using shared wet tobacco mouthpieces can cause bacterial infection including alpha-hemolytic Streptococcal pneumonia, which can manifest with bilateral upper lobe thick-walled cavities clinically resembling tuberculosis. This uncommon cause of cavitary lung disease should be considered in patients who frequent hookah bars, particularly when standard TB and fungal workups are negative and there is a history of hookah use. Improvement with appropriate antibiotics confirms the bacterial rather than mycobacterial or fungal etiology.

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