CTICasesPneumocystis jirovecii Pneumonia
Imaging findings
CT chest shows diffuse, geographic ground-glass opacities with sharp boundaries against spared lung lobules and subpleural sparing, without significant crazy paving. The patient is immunocompromised, having been treated with methotrexate for rheumatoid arthritis.
Key takeaways
Pneumocystis jirovecii pneumonia (PCP) in non-HIV immunocompromised patients can present with acute respiratory symptoms and a geographic distribution of ground-glass opacities on CT, often with subpleural sparing. Unlike PCP in HIV patients, it can develop rapidly and is associated with significant inflammatory response.
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