CTICasesPulmonary alveolar proteinosis
Imaging findings
Chest CT shows geographic, bilateral areas of ground-glass opacities with superimposed interlobular septal thickening (crazy-paving pattern) and sharp margination against uninvolved lobules. Bronchoalveolar lavage yielded milky fluid, confirming pulmonary alveolar proteinosis.
Key takeaways
Pulmonary alveolar proteinosis is a rare disease characterized by alveolar accumulation of surfactant. The classic imaging finding is a geographic 'crazy-paving' pattern with sharp margination, and treatment consists of therapeutic whole-lung lavage.
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