CTICasesMalignant Solitary Fibrous Tumor of the Pleura
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Imaging findings
Chest CT shows a large, lobulated, pleural-based soft tissue mass in the right hemithorax containing central calcifications. An initial fine-needle aspiration at an outside institution was falsely interpreted as cryptococcus. Resection of the mass reveals a solitary fibrous tumor of the pleura with histopathological features indicative of malignancy.
Key takeaways
Solitary fibrous tumors of the pleura are mesenchymal neoplasms that are usually benign and discovered incidentally, but can occasionally be malignant. They can contain central dystrophic calcifications. Fine-needle biopsy can be misleading due to technical artifacts or sampling issues, necessitating complete surgical excision for both definitive diagnosis and treatment.
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