CTICasesLeukemic Infiltrates in the Lung (Myeloid Sarcoma)
Imaging findings
CT reveals numerous septal lines throughout the lungs, along with some centrilobular opacities, atelectasis, and coarse lung consolidation in the bases. These findings were present despite the patient not being volume overloaded.
Key takeaways
Leukemic infiltration of the lung, particularly in acute myeloid leukemia (AML) with a monocytic component (M5 form), can cause diffuse lung disease. Imaging findings like prominent septal lines, usually associated with interstitial edema, can instead represent widespread infiltration of the lung interstitium by leukemia cells (myeloid sarcoma or chloroma). This can be a significant cause of dyspnea and may be confirmed at autopsy.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Hantavirus Pulmonary SyndromeInfection
- Disseminated Mycobacterium Tuberculosis in HIV-Positive PatientInfection
- Pneumocystis jirovecii Pneumonia (PJP) and Cryptococcosis in AIDSInfection
- Invasive Fungal Infection (Aspergillosis) with Diffuse Pulmonary HemorrhageInfection
- Tuberculous Chest Wall Abscess / Empyema NecessitansInfection
- Acute Histoplasmosis with Pulmonary InfarctInfection
- Aluminum-Induced Alveolar ProteinosisExposure
- Squamous Cell Carcinoma of the Lung with Small Bowel PerforationNeoplastic
See all cases from July 24, 2016 →