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Disseminated plasmacytomas causing small bowel intussusception

Imaging findings

Chest radiograph shows a left paraspinal/medial basal mass. CT scan shows multiple large, enhancing soft tissue masses in the paraspinal space, adrenal gland, breast, and omentum/peritoneum, with a bowel-wall mass acting as a lead point for small bowel intussusception.

Key takeaways

Multiple myeloma can rarely present with widespread extramedullary plasmacytomas in the soft tissues, mimicking metastatic carcinoma or lymphoma. When presenting with acute abdominal pain, lead-point intussusception from a bowel plasmacytoma should be considered.

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