CTICasesKartagener Syndrome
Imaging findings
Chest radiograph and chest CT demonstrate dextrocardia, with mirror-image arrangement of the thoracic and abdominal organs (situs inversus totalis). There is associated bronchial wall thickening, mucus impaction, and severe bronchiectasis in the lung bases, along with chronic mucosal thickening and fluid in the paranasal sinuses.
Key takeaways
Kartagener syndrome is a primary ciliary dyskinesia variant characterized by the classic triad of situs inversus totalis, bronchiectasis, and chronic sinusitis. It is caused by congenital ciliary dysmotility, which impairs normal embryogenesis (disrupting normal right-left rotation on day 19) and ciliary clearance in the respiratory tract.
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