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Thymic Calcification Post-Chemotherapy

Imaging findings

Follow-up chest CT shows diffuse, amorphous calcification throughout the thymus following chemotherapy for GI cancer. There is no calcification in the spleen, adrenals, or other tissues.

Key takeaways

Diffuse thymic calcification is a rare phenomenon that can occur after chemotherapy or severe stress (e.g., burns) and is thought to precede rebound thymic hyperplasia.

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