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Flipped Pacemaker Generator (Twiddler Syndrome Variant)

Imaging findings

Serial chest radiographs in a patient with a recently implanted pacemaker demonstrate migration and 180-degree rotation of the generator along the vertical (cranial-caudal) axis, resulting in a mirror-image appearance of the generator. The lead wires show a loop but remain securely positioned in the heart chambers.

Key takeaways

Pacemaker twiddler's syndrome is a malfunction characterized by the patient's conscious or unconscious manipulation of the generator, leading to rotation and coiling of the lead wires around the device, often causing lead displacement. A variant involves the generator flipping 180 degrees along the vertical axis within a spacious pocket, which may not cause lead dislodgement but can interfere with device programming or function.

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