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Twiddler's syndrome (pacemaker lead retraction)

Imaging findings

Serial radiographs demonstrate progressive coiling, twisting, and retraction of the pacemaker leads back into a large, capacious subcutaneous generator pocket, leading to lead malfunction.

Key takeaways

Twiddler's syndrome involves the unintentional or intentional manipulation of a pacemaker generator in its pocket, causing the device to rotate and wrap the leads around itself, leading to lead retraction, dislodgement, and loss of capture.

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