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Apical Opacity of Proto (Subclavian Artery Pseudotumor)

Imaging findings

In a patient with a history of irradiated and resected lower extremity sarcoma undergoing screening, chest radiograph shows a faint nodular opacity in the right apex with a fainter mirror-image opacity on the left. CT correlation shows that this opacity corresponds to the normal subclavian/brachiocephalic artery as it courses toward the chest wall, indenting the adjacent lung and producing an ill-defined, fuzzy apical opacity, more pronounced on the right than the left.

Key takeaways

This is the apical opacity of Proto, a normal-anatomy pseudotumor caused by the subclavian or brachiocephalic artery indenting the lung apex near the first rib, originally described by Proto in the plain-film literature of the 1970s-80s before routine CT correlation was available; recognizing this entity, along with Proto's related description of extrapleural fat producing a pseudo-superior-accessory-fissure arc, prevents mistaking normal vascular anatomy for a true apical lung lesion.

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