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Resolved Transcatheter Aortic Valve Replacement (TAVR) Leaflet Thrombosis

Imaging findings

Cardiac CT one month after transcatheter aortic valve replacement (TAVR) demonstrates extensive thickening and restricted motion of all three bioprosthetic valve leaflets, consistent with multi-leaflet thrombosis. A follow-up scan after a few months of anticoagulation therapy shows complete resolution of the thrombus with normal leaflet thickness and restoration of normal leaflet motion.

Key takeaways

Subclinical leaflet thrombosis is a recognized complication of bioprosthetic aortic valves, including TAVR, which can lead to elevated transvalvular gradients and early valve degeneration. Multi-detector CT (MDCT) is highly sensitive for identifying hypo-attenuating leaflet thickening (HALT) and hypo-attenuation affected motion (HAM), which typically respond well to oral anticoagulation therapy.

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