CTICasesInflammatory Myofibroblastic Tumor of the Lung
Imaging findings
CT chest in a young patient shows a small, well-circumscribed, non-calcified nodule in the left upper lobe. Pathological examination post-resection confirmed an inflammatory myofibroblastic tumor (IMT) with ALK gene rearrangement.
Key takeaways
Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm composed of myofibroblastic spindle cells and an inflammatory infiltrate. IMT commonly harbors ALK gene rearrangements (rearrangements of the anaplastic lymphoma kinase gene), making them responsive to ALK inhibitors like crizotinib.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Malignant Phyllodes Tumor of the Chest WallNeoplastic
- Intrapleural Silicone LeakIatrogenic
- Pulmonary Capillary HemangiomatosisVascular
- Endocardial FibroelastosisCongenital
- Cardiac AngiosarcomaNeoplastic
- Inferior Vena Cava Intramural HematomaVascular
- Cocaine-Induced Pulmonary HemorrhageExposure
- Mediastinal Yolk Sac Tumor in Klinefelter SyndromeNeoplastic
See all cases from June 26, 2020 →