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Aspergilloma in a Post-TB Cavity

Imaging findings

A patient with a history of tuberculosis shows volume loss, cavitary lesions with fluid levels, and an intracavitary mass with internal bubbles and dependent fronds, suggestive of an aspergilloma. Follow-up imaging after 6 months of posaconazole shows a reduction in the size of the aspergilloma.

Key takeaways

Aspergillomas, traditionally managed via surgical resection or toxic systemic antifungals, may show a positive response to newer antifungal agents like posaconazole with improved bioavailability.

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