CTICasesMicropapillary Lung Adenocarcinoma
Imaging findings
CT chest shows a small, necrotic, cavitary nodule in the left lower lobe with pleural tags. Pathological examination of the lobectomy specimen demonstrated extensive lymphovascular invasion and separate microscopic tumor nodules at the visceral pleural surface.
Key takeaways
Micropapillary adenocarcinoma is a highly aggressive histopathological subtype of lung adenocarcinoma. It is associated with a high rate of lymphovascular invasion, pleural invasion (upstaging the tumor to Stage IV/M1a), and a poor prognosis, even when presenting as a small, seemingly localized nodule on CT.
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