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Calcified In Situ Pulmonary Artery Thrombus

Imaging findings

Chest radiograph in a patient with a history of pulmonary embolism shows a discrete clump of calcium, initially suggesting histoplasmosis in an endemic region. The left lower lobe pulmonary artery appears wispy, with small vessels and darker lung at that site. CT localizes the calcium to within the pulmonary artery itself, with additional calcified foci more distally on the left and a smaller focus on the right. The pulmonary artery is not markedly dilated despite pulmonary hypertension, and there is modest right ventricular enlargement with septal flattening.

Key takeaways

Calcification within a pulmonary artery raises concern for calcified tumor, but thrombectomy here confirmed heavily calcified thrombus rather than tumor. Embolic or in situ thrombus can calcify in place over time, and calcification at more than one site suggests repeated episodes; proximal accumulation may follow when chronic distal disease has already made the circulation sluggish. Predisposing factors for calcification such as renal failure are worth checking. Calcified pulmonary arterial thrombus visible on a plain radiograph is rare, and regional vascular pruning with asymmetric lung attenuation is a useful corroborating sign.

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