CTICasesPeriostitis in Malignant Pleural Effusion
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Imaging findings
The patient with metastatic adenocarcinoma demonstrated an unusual and robust periostitis of the ribs adjacent to a chronic malignant pleural effusion. There was no history of radiation to the site, and the appearance was quite focal and bizarre, suggesting that the exuberant bone formation was likely a reactive response to chronic inflammation or localized tumor invasion/healing.
Key takeaways
Exuberant periostitis can occasionally develop in the ribs adjacent to malignant pleural effusions, even without prior radiation. This reactive bone formation may be a rare response to chronic inflammation or a sequela of tumor-related involvement.
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