CTICasesAmiodarone pulmonary toxicity
Imaging findings
Chest radiograph shows upper-zone-predominant consolidations, and CT chest confirms geographic areas of ground-glass opacity and consolidation with spared lobules and perilobular thickening (organizing pneumonia pattern), associated with high attenuation of the liver on unenhanced views.
Key takeaways
Amiodarone-induced pulmonary toxicity is a classic drug-induced lung injury that can manifest as an organizing pneumonia pattern. It can occur idiosyncratically or be triggered by dose increases. A high-density liver on CT due to iodine accumulation is a key diagnostic clue for amiodarone exposure.
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