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Coronary peri-arteritis in IgG4-related systemic disease

Imaging findings

CT scan shows extensive, tumor-like soft-tissue infiltration wrapping around the left anterior descending (LAD) coronary artery and its branches, which is stable to slightly increased over several years of immunosuppression.

Key takeaways

IgG4-related disease can cause peri-arterial soft-tissue infiltration ('peri-arteritis') affecting systemic vessels, including the coronary arteries. It can mimic vasculitis or aneurysm and requires systemic immunosuppressive therapy.

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