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Disseminated Mycobacterium avium complex (MAC) in HIV

Imaging findings

CT scan of an HIV patient shows right middle lobe collapse with bronchiectasis and massive, bulky mediastinal and abdominal lymphadenopathy. Many abdominal nodes display low-attenuation necrotic centers. Biopsy of a mediastinal node and BAL culture grew MAC.

Key takeaways

In patients with advanced HIV/AIDS, disseminated MAC infection can present with massive abdominal and mediastinal lymphadenopathy featuring necrotic (low-attenuation) centers and associated middle lobe bronchiectasis.

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