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Disseminated coccidioidomycosis with vertebral osteomyelitis and epidural abscess

Imaging findings

CT scan of a 31-year-old male shows right upper lobe consolidation and a large paravertebral abscess extending into the mediastinum, associated with T-spine vertebral destruction, compression fracture, and epidural extension.

Key takeaways

Coccidioidomycosis can disseminate to the skeletal system, causing osteomyelitis, discitis, and paraspinal/epidural abscesses. Direct extension from the lung into the spine or mediastinum can mimic aggressive malignancies.

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