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Cystic Thymoma with Myasthenia Gravis in an Atypical Location

Cystic Thymoma with Myasthenia Gravis in an Atypical Location▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A 22-year-old presented with a cystic lesion in the right cardiophrenic angle, adjacent to the right atrium, which had a soft tissue nodule at its inferior portion. PET demonstrated avid FDG uptake in the nodular component and rim uptake in the cystic lesion. Resection confirmed a cystic thymoma. The patient's presenting symptom was leg weakness due to myasthenia gravis.

Key takeaways

This is an unusual presentation of cystic thymoma in a young patient, occurring in the atypical right cardiophrenic angle. It underscores that thymomas, even cystic ones, can occur in younger individuals and be associated with paraneoplastic syndromes like myasthenia gravis, presenting with diverse symptoms such as leg weakness.

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