Granulomatosis with Polyangiitis (GPA) with Alveolar Hemorrhage
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Imaging findings
Radiograph showed multifocal consolidation. CT revealed areas of consolidation, air bronchograms, and large areas resembling 'reverse halos,' alongside some ground glass opacities. The patient had peripheral eosinophilia and a positive C-ANCA. A skin lesion biopsy was read as Wegener's (Granulomatosis with Polyangiitis).
Key takeaways
This case demonstrates Granulomatosis with Polyangiitis (GPA) presenting with a subacute course leading to alveolar hemorrhage. Imaging findings of consolidation with air bronchograms and reverse halos, coupled with peripheral eosinophilia and positive C-ANCA, are characteristic. Skin biopsy can also confirm the diagnosis.
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