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Multicentric Castleman's Disease

Imaging findings

Contrast-enhanced CT shows massive, hypervascular, and intensely enhancing lymphadenopathy in the anterior mediastinum, bilateral axillae, and cervical regions, associated with bilateral pleural effusions. Pathology confirmed mixed hyaline vascular/plasma cell type.

Key takeaways

Multicentric Castleman's disease is a lymphoproliferative disorder presenting with widespread, highly vascular lymphadenopathy. The lesions enhance intensely on contrast CT, mimicking hypervascular metastases or lymphoma.

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