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Micro-papillary Lung Adenocarcinoma

Imaging findings

CT chest shows progressive, confluent nodular opacities, ground-glass halos, and small cystic spaces with extremely sharp margins in a female non-smoker. The tumor was EGFR mutation positive and histologically micro-papillary.

Key takeaways

EGFR-mutated lung adenocarcinoma (frequently seen in female non-smokers) can present with confluent, well-demarcated nodular and cystic opacities. The micro-papillary subtype carries a poor prognosis.

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