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Isolated Right Ventricular Lipoma

Imaging findings

Chest CT demonstrates a well-demarcated, homogeneous, fat-attenuating mass (-50 to -100 HU) located along the right ventricular (RV) apex and the adjacent interventricular septum. There are no associated imaging features of tuberous sclerosis, such as renal angiomyolipomas, cerebral hamartomas, or subependymal nodules.

Key takeaways

Cardiac lipomas are rare, benign, primary cardiac neoplasms that can arise in any cardiac chamber. When fatty lesions are detected in the myocardium, the differential diagnosis should include tuberous sclerosis (as rhabdomyomas can undergo fatty metamorphosis) and lipomatous hypertrophy of the interatrial septum, although isolated cardiac lipomas can occur sporadically in patients with no underlying systemic disease.

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