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Primary Cardiac Diffuse Large B-Cell Lymphoma

Imaging findings

CT demonstrates a large, infiltrative, hypoattenuating mass centered in the right atrioventricular groove, directly involving the myocardium and surrounding adjacent cardiac chambers. Abdominal imaging also showed massive, bilateral adrenal masses. Biopsy and autopsy confirmed diffuse large B-cell lymphoma.

Key takeaways

Lymphoma of the heart typically presents as a large, infiltrative mass centered in the right atrioventricular groove. Unlike angiosarcoma, which is the major differential diagnosis in this location, cardiac lymphoma typically does not derive its blood supply from hyper-dilated coronary arteries.

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