CTICasesCongenitally Corrected Transposition of the Great Arteries
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Imaging findings
Contrast-enhanced CT reveals an abnormal relationship of the great vessels, with the aorta arising anterior and to the left of the pulmonary artery. The systemic venous blood flows from the right atrium into a morphologically left ventricle (which is the functional right ventricle) supplying the pulmonary artery. The pulmonary venous blood returns to the left atrium and enters a morphologically right ventricle (the functional left ventricle) that is characterized by coarse trabeculations, a moderator band, a muscular infundibulum, and an apically displaced tricuspid valve, which then pumps into the transposed aorta.
Key takeaways
Congenitally corrected transposition of the great arteries (L-TGA) is a rare form of congenital heart disease characterized by both atrioventricular and ventriculoarterial discordance, which functionally "corrects" the transposition so that oxygenated blood still reaches the systemic circulation. Though often diagnosed in childhood, some patients remain asymptomatic and are diagnosed incidentally in adulthood, where they may eventually present with progressive systemic (right) ventricular failure, tricuspid regurgitation, or conduction blocks.
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