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Asymmetric Pneumocystis jirovecii Pneumonia

Asymmetric Pneumocystis jirovecii Pneumonia▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph shows asymmetric opacities in the left lung compared to the right, along with small cystic spaces. CT of the chest demonstrates striking, highly asymmetric ground-glass consolidation primarily in the left lung, several small cystic foci, bronchial wall thickening, and a large, complex, thick-walled cavitary lesion centered in the lingula that does not directly communicate with the bronchus.

Key takeaways

Pneumocystis jirovecii pneumonia (PJP) typically presents with bilateral, symmetric ground-glass opacities, but it can manifest asymmetrically and can be associated with thin- or thick-walled cysts and pneumatoceles. In immunocompromised patients with AIDS, complex cavitary or mass-like presentations should raise suspicion for PJP or superimposed infections, and diagnosis is typically confirmed via bronchoscopy.

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