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Granulomatosis with Polyangiitis presenting as Isolated Subglottic Tracheal Stenosis

Imaging findings

Chest CT and coronal reformats demonstrate focal subglottic tracheal stenosis. Mild apical scarring and subtle basilar fibrosis are also present. Bronchoscopy confirms significant concentric narrowing of the subglottic airway, which was treated with thermal or laser ablation to restore airway patency.

Key takeaways

Granulomatosis with polyangiitis (GPA) can manifest as isolated subglottic tracheal stenosis, occasionally in the absence of active lung parenchymal disease or systemic symptoms. Radiologists should maintain GPA in the differential diagnosis for focal upper airway narrowing, especially in patients with a history of systemic autoimmune disease or unexplained renal impairment.

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