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Eosinophilic Granulomatosis with Polyangiitis (EGPA)

Imaging findings

CT of the chest reveals multiple well-defined pulmonary nodules, some showing central air bronchograms, alongside extensive, patchy, upper-lung predominant consolidation and ground-glass opacities, accompanied by a pleural effusion.

Key takeaways

Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome) is a systemic necrotizing vasculitis that typically affects small-to-medium vessels in patients with asthma and peripheral eosinophilia. Pulmonary findings include transient non-segmental consolidations representing eosinophilic pneumonia, and nodules which may occasionally cavitate.

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