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Diffuse In-Situ Pulmonary Artery Thrombosis

Imaging findings

CT in a 37-year-old female with severe hypoxia shows a large right atrial thrombus, a left atrial posterior wall thrombus, and diffuse, bilateral lower lobe pulmonary artery non-perfusion/infarction due to severe in-situ arterial thrombosis.

Key takeaways

Severe systemic hypercoagulability can cause diffuse, bilateral in-situ pulmonary artery thrombosis and biventricular thrombi in transit. This leads to massive lobar non-perfusion and pulmonary infarction, presenting with profound, life-threatening hypoxia.

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