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Invasive Pulmonary Scedosporiosis

Imaging findings

Peripheral nodular consolidation with halos, progressing to worsening consolidation in the lower lobes, in a neutropenic patient despite broad-spectrum antifungals.

Key takeaways

Scedosporium (formerly Pseudallescheria boydii) is an angioinvasive fungal infection that can mimic aspergillosis, causing rapidly progressive nodular lesions with halos in immunosuppressed patients. It requires specific antifungal treatment, such as voriconazole, due to variable susceptibility to standard broad-spectrum agents.

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