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Leukemic Infiltration of Myocardium and Pericardium

Imaging findings

A large pericardial effusion and diffuse abnormal signal throughout the myocardium are noted on cardiac imaging. PET scan demonstrates complete and extensive FDG uptake within the heart, indicative of widespread infiltration.

Key takeaways

Leukemic infiltration of the myocardium and pericardium can present with pericardial effusion and diffuse myocardial involvement, which is impressively demonstrated on PET imaging by widespread metabolic activity. Autopsy confirms the infiltrative nature of the disease.

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