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Nodular Lymphoid Hyperplasia

Imaging findings

CT chest shows multiple, stable pulmonary nodules containing internal bubbly lucencies (cystic spaces) followed over 5.5 years. Biopsy confirmed polyclonal lymphoid hyperplasia without malignancy.

Key takeaways

Nodular lymphoid hyperplasia is a benign, reactive lymphoproliferative disorder of the lung. It typically presents as stable nodules that can contain internal bubbly lucencies/air bronchograms, mimicking MALT lymphoma or adenocarcinoma.

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