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Methamphetamine-Induced Coronary Artery Vasospasm and Myocardial Infarction

Imaging findings

Cardiac MRI steady-state free precession (SSFP) and delayed enhancement images show septal akinesis, paradoxical septal motion, transmural myocardial infarction in the LAD territory, and a non-enhancing apical thrombus. Coronary catheterization confirmed occlusion of the LAD with a small septal perforator.

Key takeaways

In young patients presenting with acute coronary syndrome or myocardial infarction, methamphetamine-induced vasospasm is a critical diagnostic consideration. These patients often have a history of heavy consumption of high-sugar sodas to manage low sugars while high on meth, which can be a clinical clue (destroyed teeth).

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