CTICasesInhalational talcosis presenting as hypersensitivity pneumonitis
Imaging findings
CT scan demonstrates extensive, ill-defined centrilobular nodules with ground-glass opacities and mosaic attenuation, sparing the subpleural surfaces, which progressed to confluent areas of consolidation. Lung biopsy confirmed talcosis with polarizable talc crystals and interstitial granulomas.
Key takeaways
Daily inhalation of cosmetic talcum powder can cause inhalational talcosis, which manifests radiographically and histologically as a hypersensitivity pneumonitis-like reaction or granulomatous disease.
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