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Vaping-associated desquamative interstitial pneumonia (DIP)

Imaging findings

CT scan of a chronic vaping patient shows lower-lobe predominant ground-glass opacities, reticulation, bands of consolidation, and traction bronchiectasis. Surgical biopsy confirmed desquamative interstitial pneumonia (DIP) and respiratory bronchiolitis (RB-ILD) patterns.

Key takeaways

DIP is characterized by alveolar accumulation of pigmented macrophages. Although classically associated with cigarette smoking, it can also be seen in patients who vape THC/marijuana or are exposed to other inhaled toxins, and can show clinical improvement following cessation.

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