CTICasesTuberous Sclerosis Complex
Imaging findings
CT chest shows multiple, thin-walled, round cysts distributed symmetrically throughout the lungs. Abdominal CT shows bilateral renal angiomyolipomas. Spine CT shows multiple, discrete sclerotic bone lesions ('bone islands') within the vertebral bodies.
Key takeaways
Tuberous sclerosis complex (TSC) frequently manifests with pulmonary cysts identical to lymphangioleiomyomatosis (TSC-LAM). Sclerotic bone lesions in the spine and renal angiomyolipomas are crucial imaging discriminators that distinguish TSC-LAM from sporadic, isolated LAM.
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