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Pulmonary tumor thrombotic microangiopathy from esophageal cancer

Imaging findings

CT scans obtained months apart in a patient with esophageal cancer demonstrate new, progressive, multifocal, multilobar, small peripheral branching tubular opacities. There is a visible intravascular component with distension of small segmental and subsegmental pulmonary artery branches by intraluminal material without significant enhancement, representing intravascular tumor emboli.

Key takeaways

Pulmonary tumor thrombotic microangiopathy is a rare, severe complication of malignancy, such as esophageal cancer, characterized by tumor emboli within the pulmonary vasculature. Radiographically, it manifests as small, tubular branching centrilobular or peripheral vascular opacities, which can be misdiagnosed as aspiration pneumonia.

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